Part 1: understanding pandemics and epidemics. The pandemic threat: why it matters ; Outbreaks, epidemics, and pandemics ;Concepts of occurrence, progression, and spectrum of disease ; Chain of infection ; Deadliest outbreaks and pandemics in history ; Factors in the emergence of infectious diseases ; One health initiative ; Notable pseudopandemics of the last century ; Bioterrorism and the pandemic potential -- Part 2: Major pandemics and epidemics. HIV/AIDS ; Chikungunya ; Cholera ; Coronaviruses ; Ebola ; Influenza ; Malaria ; Meningitis ; Nipah virus infection ; Smallpox ; Tuberculosis ; Yellow fever ; Zika -- Part 3: principles of disease management. Preventing avoidable epidemics ; Antimicrobial drug resistance and emerging infectious disease ; Hospital-based infections ; Laboratory-guided detection of disease outbreaks ; Disease surveillance ; Role of technology and surveillance systems in public-health response ; Disease control and containment ; Developing interventions ; Pharmacological interventions: medical countermeasures ; Community mitigation interventions -- Part 4: the next pandemic: are we ready? Getting ahead of the next pandemic ; The 1918 flu pandemic: why it matters 100 years later ; Viruses of special concern ; Getting your household ready for pandemic flu ; The national pandemic strategy ; Strategic stockpiling for the next influenza pandemic ; Global health security: prevent, detect, and respond to global health threats ; A look back at the progress since the 2009 H1N1 pandemic -- Part 5: additional help and information. Glossary of terms associated with outbreaks, epidemics, and pandemics ; Directory of organizations.